Endocrine Abstracts

Introduction: Early prediction of anticancer therapy cardiotoxicity is essential for applying proper preventive and supporting therapeutic strategies.Objective: To evaluate plasma N-terminal fragment of pro-brain natriuretic peptide (NT-proBNP) related to cardiac dysfunction assessed by transthoracic 2D echocardiography (2D-TTE) in patients with cancer and early onset asymptomatic anthracycline-induced cardiomyopathy (AIC).Methods:...

Background: Risk stratification could be lifesaving in acute pulmonary embolism (PE). Echocardiographic (ECHO) acute right ventricular dysfunction (RVD) is the actual ‘gold standard’ in risk assessment of patients with PE. We previously demonstrated that plasma BNP levels were significantly higher in patients with PE and acute RVD on ECHO versus patients with normal right ventricular (RV) function on ECHO.Aim and objective: Evaluation of the li...

Introduction: The study aimed to analyze the efficiency of a concomitant N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac high-sensitivity troponin T (hs-cTnT) testing in diagnosing non-ST-segment-elevation myocardial infarction (NSTEMI) in patients initially negative for the standard fourth-generation assay of cardiac troponin T (cTnT), but with high clinical probability of non-ST-segment-elevation acute coronary syndrome (NSTE-ACS).Meth...

Background: Acute right ventricular dysfunction (RVD) on echocardiography (ECHO) is critical for risk stratification in pulmonary embolism (PE). Plasma BNP, a consecrated marker of left ventricular dysfunction, could represent a valuable biomarker of RVD in PE.Aim and objective: Assessment of plasma BNP levels in patients with PE in relationship with right ventricular (RV) function evaluated by ECHO.Methods: Prospective study of 70...

Introduction: Meigs’ syndrome is defined as the presence of a benign ovarian tumour (fibroma), in association with ascites and hydrothorax. The characteristic feature of this condition is the resolution of the effusions once the tumour is surgically removed.Case report: A 63 year-old female patient was admitted to the Surgery Clinic with metroragia, abdominal distention, and a recent history of minor breath shortness. Pulmonary clinical examination ...

Introduction: Adrenal myelolipoma is a rare benign tumour composed of mature adipose tissue and haematopoietic elements developed within the adrenal gland, usually unilateral, asymptomatic, and non-functional. Their real incidence is unknown.Case report: A 56 year-old female was admitted to our surgery department for abdominal distension and the presence of a large palpable tumour in the right abdomen discovered during an abdominal ultrasonographic check...

Introduction: Acute right ventricular dysfunction (RVD) on echocardiography (ECHO) represents the actual gold standard in risk stratification of patients with pulmonary embolism (PE). We previously demonstrated that plasma BNP above a cut-off level of 50 pg/ml could predict acute RVD in PE.Aim and objective: Analysis of the utility and accuracy of plasma BNP in detecting acute RVD in PE.Methods: Seventy patients with confirmed PE, ...

Introduction: Atheromatous plaque instability biomarkers are the most important predictors for the evolution with major acute cardiovascular events (MACE) in patients with NSTE-ACS.Objective: To evaluate the impact of dyslipidemia, endothelial dysfunction, oxidative stress, platelet hyperactivity and hypercoagulable state and their inter-correlation on the outcome of NSTE-ACS.Methods: Two hundred and forty patients with NSTE-ACS, 1...